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Geosmin synthase
Geosmin synthase or germacradienol-geosmin synthase designates a class of bifunctional enzymes that catalyze the conversion of farnesyl diphosphate (FPP) to geosmin, a volatile organic compound known for its earthy smell. The N-terminal half of the protein catalyzes the conversion of farnesyl diphosphate to germacradienol and germacrene D, followed by the C-terminal-mediated conversion of germacradienol to geosmin.〔 The conversion of FPP to geosmin was previously thought to involve multiple enzymes in a biosynthetic pathway.
== Species distribution ==
Geosmin is found in a wide variety of microbes such as cyanobacteria and actinobacteria. Geosmin has also been found in myxobacteria, fungi, arthropods, and plants such as beets. Based on studies performed on a geosmin synthase (encoded by SCO6073) in ''Streptomyces coelicor'' and the high sequence similarity between this and other known or putative geosmin synthases (45-78% identity), it has been hypothesized that all geosmin synthases function in the same manner.〔 Screening of available bacterial genomic data has resulted in the prediction of at least 55 putative geosmin synthases in this domain of prokaryotic organisms.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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